Anti-d Injections

Anti D antibody injection is given to Rh-negative mothers with Rh-positive fetuses. When the fetus' blood comes in contact with the mother's blood, D antibodies are produced in the mother's blood against the D antigens of the Rh-positive fetus (a protein present on the surface of red blood cells of Rh-positive people). This is known as sensitization. These antibodies pose a risk to the second child (if Rh positive), leading to hemolytic disease of the newborn (erythroblastosis fetalis), jaundice, anemia, etc. To prevent this, the anti D injections are given to the Rh-negative mother (with Rh-positive partner) in the 24th and 38th week of pregnancy or anytime after sensitization. These injections do not pose any complications to both mother and the baby.

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All the answers published in this website are written by Verified medical doctors, therapists and health experts. The Content has been moderated by iCliniq medical review team before publication. Post your medical clarifications on iCliniq by choosing the right specialty and get them answered. Your medical queries will be answered 24/7 by top doctors from iCliniq.

Could my negative blood group cause any pregnancy complication?

Query: Hello doctor, I am 3 months pregnant. My blood group is O negative. Will I face any complication during pregnancy due to my negative blood group? I consulted with my doctor, and she told me to take Fertigyn 5000 injection once a week for four weeks. Is it safe? Will it make me get a normal delivery ...  Read Full »


Dr. Aishwarya Parthasarathy

Answer: Hi, Welcome to icliniq.com. When there is a negative blood group, there will be attacking agents for positive blood group in your blood called antibodies. In case your partner is positive, then there are chances of your baby being positive. The first child usually escapes, and in the case o...  Read Full »

Why was anti-D injection given after my second abortion?

Query: Hello doctor, I am a 24-year-old female. I have undergone two medical abortions one at the age of 22 and at 24. I have Rh negative blood group. I was not given an anti-D injection the first time but I was given the second time. The doctor suggested an ICT test and it came positive which means ther...  Read Full »


Dr. Aishwarya Parthasarathy

Answer: Hello, Welcome to icliniq.com. Rh-negative pregnancy occurs when there is negative blood group in the mother and positive in the unborn child. The attacking agents called antibodies are produced by the mother which crosses the placenta and attacks the child. Usually, the first pregnancy is spared...  Read Full »

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