Anti Tubercular Drugs

A multidrug regimen is followed to treat tuberculosis, which can be either first-line drugs or second-line drugs. First line drugs are given for new patients of TB, and the drugs include Isoniazid, Rifampin, Pyrazinamide, and Ethambutol. Second line drugs are used in case of drug-resistant TB, the drugs like Fluoroquinolones, Amikacin, Kanamycin, Linezolid, etc. are used.

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Is it right to have surgery for the compression present with bone tuberculosis?

Query: Hi doctor, My father has bone tuberculosis. He has compression in D4 to D5. He is bedridden now. Currently, he is taking medicine for TB. Is it necessary to do surgery or not? Please suggest.  Read Full »

Dr. Rahul Goel

Answer: Hi, Welcome to I have gone through the attachment (attachment removed to protect patient identity). This condition is known as pott's spine. There is a presence of tuberculosis in the spine. It is managed by taking ATT (antituberculosis medication). It is not good to have surgery duri...  Read Full »

Will my testicular infection spread to my partner through unprotected sex?

Query: Hi doctor,My left testicle is swollen, and it pains sometimes. Doctors say that there is some infection. I was prescribed with AKT-4. Three months back, my semen analysis report showed pus cells 2-4 hpf and RBC 2-4 hpf. My present report showed pus cells nil and RBC nil. Semen culture report showed ...  Read Full »

Dr. Ashok Kumar

Answer: Hi, Welcome to I read your query and understand your concerns. From the available description, it appears that you suffered from epididymo-orchitis due to tubercular infection. Although the urine culture and microscopy report showed all normal, it is advisable to use protection while ...  Read Full »

What does my child's Mantoux test indicate?

Query: Hi doctor, My kid is 2.5 years old. She keeps getting cough and cold every month. She is very sensitive to weather change. We consulted a local doctor and he advised for Mantoux test. The report says that the erythema and induration developed around 18x16 mm area after 48 hours. What does it mean? A...  Read Full »

Dr. Deepak Patel

Answer: Hi, Welcome to Recurrent episodes of cough and cold occur when the child has decreased immunity due to some illness or it could be a symptom of tuberculosis. Mantoux test of more than 10x10 mm is suggestive of tuberculosis. In your child, it is 18x16 mm which is strongly positive. In tu...  Read Full »

Should I continue medicines for bone tuberculosis even if I do not have any symptoms?

Query: Hi doctor, This question is about medicine duration for bone TB treatment. I was having left hip pain, and MRI showed mild synovitis in the left hip one year ago. The medication was initially started suspecting bone TB. There was a repeat MRI after four months of completion of medicine and everythin...  Read Full »

Dr. Atul Prakash

Answer: Hello, Welcome to The answers to your questions are as follows: 1) Duration of treatment is nine months and you have exceeded that, the only need to extend treatment is if the symptoms or if blood parameters are raised. In your case, symptoms, CRP, and ESR are normal. 2) No if the s...  Read Full »

Is it normal to have pain while taking AKT-4 kit and Benadon 40 for TB?

Query: Hello doctor, I am a 22-year-old female. I got effusion in my right chest and was detected with pulmonary TB. I have been prescribed with AKT-4 kit and Benadon 40 mg for one month. I am taking this medication for the last five days and am feeling pain in my chest and rib area during breathing for p...  Read Full »

Dr. Pawar Satyajit Jalinder

Answer: Hello, Welcome to I would like to ask a few questions. What were your symptoms and since when you were symptomatic? How was TB (tuberculosis) diagnosed and based on what tests? I am asking this because, though in more than 90 % cases effusion is due to TB, there can be other cau...  Read Full »

I am diagnosed with latent TB without any symptoms. Are the prescribed TB medications safe?

Query: Hello doctor, I have been diagnosed with latent TB and was prescribed medications for it. I have attached a copy of the reports below. I want to consult a specialist before I start my prophylactic course.  Read Full »

Dr. Sugreev Singh

Answer: Hello, Welcome to Thank you for writing, and I understand your concern. I have gone through your reports (attachments removed to protect the patient's identity). It is suggestive of TB (tuberculosis), but before starting the treatment, you should get a chest x-ray, LFT (liver function...  Read Full »

What is the recommended course of action for high CRP level?

Query: Hello doctor, I have Potts disease, and after two months, my C-reactive protein has gone from 48 to 96. What further course of action should I take?  Read Full »

Dr. Palani Kumar Chellamuthu

Answer: Hello, Welcome to Your Pott's disease, I assume, is being treated with an anti-tuberculosis drug cocktail (dosage accurately adjusted according to your body weight). The spine surgeon can decide on healing and response to treatment based on your clinical response like a decrease in pa...  Read Full »

I am on antitubercular drugs Akurit 4. Can I take Silymarin syrup for liver protection?

Query: Hello doctor. I am 31 years old. Recently I have been diagnosed with tubercular lymphadenitis and I have been taking the anti-tubercular medicine Akurit 4 for one week. I have done Hb electrophoresis by HPLC method test where along with other values HbA1c % was shown 4.8 %. Is it the same HbA1c that...  Read Full »

Dr. Sagar Ramesh Makode

Answer: Hello, Welcome to I understand your concern. 1. It is the same which is used in diabetics and it is normal. In the attached report, (the report has been removed to maintain the privacy of the patient) HbA2 is elevated and it is an indicator of beta thalassemia carrier. 2. There are no c...  Read Full »

I coughed blood and am being treated for TB. I need expert advise.

Query: Hello doctor, I was positive for hepatitis B four years ago, and recently I was rushed to the hospital for coughing up blood from my lungs. The CT chest shows that there are some bleeding areas in my lungs. The Gene expert test shows that I have very low tuberculosis. My kidneys are normal and my li...  Read Full »

Dr. Pawar Satyajit Jalinder

Answer: Hello, Welcome to As your gene Xpert report (attachment removed to protect patient identity) shows you have been tested positive for MTB which is sensitive to Rifampicin. Means you have pulmonary tuberculosis and it is sensitive to first-line drugs. The standard treatment in this case...  Read Full »

My mother is becoming very tired after taking anti-TB tablets. Please help.

Query: Hello doctor, I have started anti-TB schedule 13 tablets for my mother of age 70 years, as she was detected right pleural effusion and certain pleural fluid was sent to the lab for analysis and gene Xpert test came negative. Still, the problem is now I have started the TB tablets, which make her fee...  Read Full »

Dr. Kaushal Bhavsar

Answer: Hi, Welcome to I can understand your concern. In my opinion, I suggest her taking start antacid with an anti-emetic combination like Pan D (Domperidone 30 mg and Pantoprazole 40 mg) or Nexpro RD (Domperidone 30 mg and Esomeprazole 40 mg) twice daily before breakfast and dinner. Take ade...  Read Full »

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