Hemoglobin A

Hemoglobin A, where A stands for adults, is the widely prevalent hemoglobin tetramer that contains two alpha and two beta subunits. The subunits have a heme group for the binding oxygen molecules, which aids in oxygen transportation from the tissues to the lungs. Deficiency of hemoglobin A results in alpha-thalassemia, beta-thalassemia, and sickle cell anemia.

  
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Is my friend's beta thalassemia screening test seem normal?

Query: Hello doctor,My cousin of 30 years old got tested for beta thalassemia screening test. He got the result as hemoglobin A2 is 2.8 %, hemoglobin F is 0.2 %, and hemoglobin C, D, and S are not detected. Is this normal or has any complications?Please guide.  Read Full »


Answer: Hi, Welcome to icliniq.com. Based on your query, my opinion is as follows: The beta-thalassemia screening test appears to be normal. HbA2 levels (hemoglobin A2) are normally between 2 to 3.3% and HbF levels (fetal hemoglobin) are 0.1 to 1.2% for this age. Both are normal. The other hemoglobin typ...  Read Full »

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