Motor Neuron Disease

Motor neuron disease, also called amyotrophic lateral sclerosis (ALS), is a progressive neurological disorder that affects the nerve cells present in the brain and spinal cord, resulting in muscle control loss. This disease usually starts as muscle twitching, limb weakness, and slurred speech. There is no cure for ALS, and in advanced stages, it can result in the loss of control of muscles needed to breathe, speak, move, and swallow.

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Can motor neuron disease only affect the extensor functions and not flexion function?

Query: Hello doctor, I am a 58-years-old male with atrophy and muscle weakness in the upper extremities for the past 17 years. Muscle weakness only affects the extension functions, not the flexion functions. I underwent a PET scan, EMG, and NCV, and the doctor diagnosed it as multifactor motor neuropathy o...  Read Full »

Dr. Florilyn Joyce Chulsi Bentrez

Answer: Hi, Welcome to I understand your concern. I have a few questions so that I can help you. 1. With extension, do you mean with the fingers and elbows? 2. Can you abduct your shoulders at a 90-degree angle? 3. Is there pain, numbness, or any sensory deficit besides motor weakness? 4...  Read Full »

I am suffering from weakness in my legs and right arm. Can it be due to ALS or MND?

Query: Hi doctor, I am a 19-year-old male. For the last couple of days, I have been extremely worried about having the early symptoms of ALS or MND. A week ago, I felt as if my whole body was tired and burnt out. Recently I have noticed my legs have become quite tired, shaky, and fatigued easily, and my ri...  Read Full »

Dr. Aida Abaz Quka

Answer: Hi, Welcome to Thanks for writing in, and I understand your concern. I suggest your symptoms are not suggestive of ALS (amyotrophic lateral sclerosis) or MND (motor neurone disease), especially after considering the normal reflexes and the short period of time of your history. So, in...  Read Full »

My little finger is deviating. Is it a split-hand sign, or do I have a motor neuron disease?

Query: Hello doctor, My left shoulder is smaller than my right and tires more easily from exercise. However, I feel pain in my wrist and the back of my palm whenever I drive. My little finger is forming a split hand sign. Does this mean ALS? Is this a split-hand sign? Why is my little finger deviating? Do ...  Read Full »

Dr. Hitesh Kumar

Answer: Helllo, Welcome to 1. When did you start to have symptoms of early tiring from exercise, and when did you start to have pain in the wrist and back of your palm while driving? 2. Since when did you notice that your left shoulder is smaller than your right? 3. Do you have difficulty i...  Read Full »

I have a tingling sensation in my feet and hands and twitching in my left eye and thighs. Do I have a motor neuron disease?

Query: Hello doctor, Two months ago, a tingling sensation started in my hands and feet more on the left side. The tingling has recently subsided, but I now have some minor twitching in my left eye and on both thighs. I have tinnitus and floaters in my eyes, which developed recently. I also have muscle weak...  Read Full »

Dr. Abhishek Juneja

Answer: Hello, Welcome to Muscle twitchings may happen in motor neuron disease. But motor neuron disease is a rare disorder. Other common causes of muscle twitching include anxiety, caffeine, nicotine, thyroid dysfunction, and diabetes. Also, twitching in isolation is generally benign unless it...  Read Full »

Are my EMG reports suggestive of ALS?

Query: Hi doctor,I want a review of EMG analysis to reassure it to be unlikely ALS onset. My knee and arm reflexes were normal, as were the strength tests. Does "good recruitment" in the presence of atrial fibrillation and occasional positive waves point away from ALS or MND? In those cases, would the recr...  Read Full »

Dr. Ashok Kumar

Answer: Hi,Welcome to read your query and understand your concerns.First of all, I would like to inform you that the available EMG (electromyography) report does not suggest anything found in motor neuron disease (attachment removed to protect the patient's identity). My observation is based o...  Read Full »

Why do I have spasms in my hand with pins and needle feeling?

Query: Hi doctor, I am having spasms in my hand. I had it briefly in the left hand and then, my right arm was feeling numb. This morning my right hand has spasms on all fingers at different occasions with some pins and needle feeling. Please help.  Read Full »

Dr. Ambekar Sudheer

Answer: Hello,Welcome to might have nerve compression from cervical spondylitis.Please consult your GP to get an MRI of the neck.For further information consult a neurologist online -->  Read Full »

What is the cause of my persistent twitches all over the body?

Query: Hello doctor, About one month ago, I started to get twitches all over my body. Everywhere from my toes and fingers to backs of my thighs, neck, and torso. They feel like small little zings and are present all day long. I have no idea why the twitching is happening. Things I have considered, I have ...  Read Full »

Dr. Hitesh Kumar

Answer: Hello, Welcome to I would like to know some further details about your symptoms: Are these twitches visible by eyes? Or these only felt by you without being seen by eyes? Have you noticed what triggers these twitches? Like when being more anxious, empty stomach, cold weather, smoki...  Read Full »

How is MND diagnosed?

Query: Hi doctor, I have recently noticed a lot of wrinkling of my skin on both my thenar muscles of the thumb. I just noticed it a month ago. I also have a dent or atrophy on the back of my right hand between the little and middle finger. I am not sure whether this is new as it seems to appear in a video ...  Read Full »

Dr. Ambekar Sudheer

Answer: Hi, Welcome to Motor neuron disease may be a possibility for the appearance of muscle atrophy in the photographs that you have sent (attachment removed to protect patient identity). However, the definitive test for MND is ENMG, which stands for electroneuromyography. It can detect wheth...  Read Full »

Can anxiety pay way for a habit of head twitch?

Query: Hello doctor, I am concerned about a head twitch. I have gotten in a habit for seven months of twitching my head. If I am consciously thinking about what I am doing, I can stop it. However, it is extremely difficult and I feel an overwhelming impulse to do it, similar to how one would feel when cra...  Read Full »

Dr. Suresh Kumar G D

Answer: Hello, Welcome to From your description, it looks like you are experiencing a motor tic. Do you have any other symptoms? How old are you at present? You mentioned this tic started befor seven months. Have you experienced any tics before? Any vocal tic? Tics can be suppressed tempora...  Read Full »

Is muscle twitching a predominant sign of motor neuron disease?

Query: Hello doctor, For about two weeks now, I have had a twitch in my left arm (triceps) that seems to be worse when I have my arm straight and down by the side of my body and less noticeable when I have my arm over my head and bent at the elbow. The twitch seems to be worse at times without any particu...  Read Full »

Dr. Upendra Kumar Shah

Answer: Hi, Welcome to This is acute onset localized twitches, started after strenuous activity. This seems to be physiological twitches that are occurring due to minor muscle or nerve injury. Just check for any weakness or loss of muscle mass in the region where you are developing twitches...  Read Full »

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