Polycythemia Vera

Polycythemia vera is a slowly progressive and rare blood cancer where the bone marrow produces a lot of red blood cells. This excess red blood cells thicken the blood and cause the blood to flow slowly. It can cause blood clots that can result in heart attack and stroke.

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What is the reason for the increase in Hb and Hct values in me?

Query: Hi doctor, I am really worried that my Hgb is 17.6 and Hct is 54.6. I have been recommended to consult a hematologist in cancer care center. I am bothered whether it is a major illness. Can you please help me out?  Read Full »


Dr. Prakash H Muddegowda

Answer: Hi, Welcome to icliniq.com. Based on your query, my opinion is as follows: Your hemoglobin (Hb or Hgb) and hematocrit (Hct) is a bit high and hence further evaluation is being done. If you are from a hill station or a smoker or with lung disorder then this may be normal. This is called as polycythe...  Read Full »

What is the reason for decreased T4 and increased TSH levels in blood?

Query: Hello doctor, I got a blood test done recently. In the reports, which I have attached, most of my results are fine, but some major concerns are my vitamin B12 level is 1477 ng/mL, T4 is 3.8, TSH is 12.63, and platelet count is 140. Is something wrong going on in my body? Are these indicating some ...  Read Full »


Dr. Parth R Goswami

Answer: Hi, Welcome to icliniq.com. I have seen your reports (attachment removed to protect patient identity). Your T4 level is low, and TSH (thyroid stimulating hormone) is high, it suggests primary hypothyroidism. For which, I suggest Levothyroxine 25 or 50 mcg daily. You also have vitamin D deficiency, ...  Read Full »

Do increased levels of RBC and vitamin B12 cause polycythemia vera?

Query: Hi doctor, My RBC levels have been slightly elevated for the past six months. It was 5.17 a year back, and a couple of months back it was 5.39. I noticed that from the last two years, the RBC count has been borderline high. Last week my vitamin B12 was tested due to a nerve issue in my face, which ...  Read Full »


Dr. Parth R Goswami

Answer: Hi, Welcome to icliniq.com. I appreciate your knowledge and awareness towards your health, and I have seen your reports (attachment removed to protect patient identity). Your vitamin B12 level is certainly high, enough that warrants further investigation. Following are the common causes for high vit...  Read Full »

I suffer from polycythemia. Can it be caused due to smoking?

Query: Hi doctor, I am a 37 year old male. I am suffering from polycythemia for the last two years. My Hb is 19.17 and HCT is 51.9. The doctors informed me that it is all due to smoking. Is there any serious problem with me? What will you suggest? Thank you.  Read Full »


Dr. Parth R Goswami

Answer: Hi, Welcome to icliniq.com. Chronic smoking can lead to heart failure, chronic lung disease, etc., and hence, polycythemia occurs. It is called secondary polycythemia. With the treatment, the prognosis is good in secondary polycythemia. But, polycythemia can occur as primary polycythemia as well, an...  Read Full »

Why do I have high hemoglobin and hematocrit values?

Query: Hi doctor, I am a 31 year old female. I have a history of celiac disease and a past medical history of Hodgkin's lymphoma, a stage 2 cervical lymph node and tumors in my chest. I had a blood test last week which showed B12 and folic acid deficiency, raised hemoglobin of 161 and raised hematocrit of ...  Read Full »


Dr. Parth R Goswami

Answer: Hi, Welcome to icliniq.com. You are having celiac disease in which because of malabsorption vitamin B12 deficiency and folate deficiency can occur. This deficiency also can be developed if polycythemia present in which proliferation more. Here hemoglobin and HCT is high as per history. Hence if it i...  Read Full »

Why is Aspirin advised for high RBC and hemoglobin count?

Query: Hi doctor, I am a 40 year old male. My hemoglobin was 18.3 g/dL, but it has come down to 17.7 g/dL since the last two months. My RBC count varies between 6.1 to 6.27 now, and PCV is 51.9 %. I am taking mini Aspirin as suggested by my doctor. Do I have any reason to worry?  Read Full »


Dr. Parth R Goswami

Answer: Hi, Welcome to icliniq.com. Your hemoglobin level, RBC (red blood cells), and PCV (packed cell volume) are high. The lymph node, liver, and spleen need to be clinically examined. Do you have a history of dizziness, weakness, and stroke? High level of RBC and hemoglobin can cause blood clots and ca...  Read Full »

Does a mild rise in hemoglobin, hematocrit, and WBC indicate polycythemia vera?

Query: Hi doctor, I have left and right-sided abdominal pain. I had bloody mucus in the stool, which has resolved, having itchy dry skin all over. Blood test says high white blood cell count, high hematocrit, high hemoglobin, and a very high ALT in the liver test. The abdominal CT scan was clear, except t...  Read Full »


Dr. Parth R Goswami

Answer: Hello, Welcome to icliniq.com. Actually, in the attached graphical report (attachments remove to protect the patient's identity), ALT (alanine aminotransferase) is not raised twofold means not elevated more than 84. So, it does not indicate liver dysfunction. In liver problems, ALT usually rai...  Read Full »

What is therapeutic phlebotomy and why is it done?

Query: Hi doctor, I am an obese person and a non-smoker. I am on an exercise program, and my weight reduced from 132 to 124 kg. I am under therapeutic phlebotomy once in three weeks (before once in two weeks). I found high counts in blood before 14 months during medical fitness blood test abroad and consu...  Read Full »


Dr. Parth R Goswami

Answer: Hello, Welcome to icliniq.com. Regular follow-up is my opinion for your question. I have seen the attached reports (attachment removed to protect the patient's identity). Your JAK2 (Janus kinase 2) report is negative, and EPO (erythropoietin) is within the limit. So polycythemia vera, like ...  Read Full »

What does high hemoglobin count indicate?

Query: Hi doctor, My hemoglobin level is 18.70, PCV 55.40, MCV 120, MCH 40.70, RDW 8.40. What should I do?  Read Full »


Dr. S D Sinha

Answer: Hi,Welcome to icliniq.com.Please share a copy of all your lab reports. These reports appear out of place.Do you have any history or diagnosis of polycythemia vera in the family or past history?  Read Full »

Will dehydration and smoking cause changes in CBC report?

Query: Hello doctor, I am a 27-year-old male. I have had dizziness, weakness and shaking, sometimes chest pain, and shortness of breath. I have stiff upper back pain, and most of my body clicks and pops when I move. I have also had a loss of appetite, like no appetite at all and weight loss. I had bad upp...  Read Full »


Dr. Parth R Goswami

Answer: Hello, Welcome to icliniq.com. In the attached report (attachment removed to protect patient identity), cholesterol level is high. For that, take a low-fat diet and do some morning exercise. In one of the attached reports, hemoglobin and PCV (packed cell volume) is high with increased RBC (red...  Read Full »

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