Polycythemia Vera

Polycythemia vera is a slowly progressive and rare blood cancer where the bone marrow produces a lot of red blood cells. This excess red blood cells thicken the blood and cause the blood to flow slowly. It can cause blood clots that can result in heart attack and stroke.

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All the answers published in this website are written by Verified medical doctors, therapists and health experts. The Content has been moderated by iCliniq medical review team before publication. Post your medical clarifications on iCliniq by choosing the right specialty and get them answered. Your medical queries will be answered 24/7 by top doctors from iCliniq.

What could be the reason for my high platelet levels?

Query: Hello doctor, I have migraines for months was put on medication, but it was not helping. Now I am on preventative and emergency medicines. I have done an MRI, which showed abnormal results. Blood work showed platelets of 544. I was asked to consult a hematologist. What can it be?  Read Full »


Dr. Kapil Gupta

General Medicine Physician, Internal Medicine Physician

Answer: Hello, Welcome to icliniq.com. I have reviewed the reports of your MRI (magnetic resonance imaging) and blood (attachment removed to protect patient identity). They are incomplete reports, and I would like you to share the other sections of the reports as well for me to have a clear picture. Well...  Read Full »

Will dehydration and smoking cause changes in CBC report?

Query: Hello doctor, I am a 27-year-old male. I have had dizziness, weakness and shaking, sometimes chest pain, and shortness of breath. I have stiff upper back pain, and most of my body clicks and pops when I move. I have also had a loss of appetite, like no appetite at all and weight loss. I had bad upp...  Read Full »


Dr. Parth R Goswami

Family Physician, General Practitioner, Hematologist, Pathologist

Answer: Hello, Welcome to icliniq.com. In the attached report (attachment removed to protect patient identity), cholesterol level is high. For that, take a low-fat diet and do some morning exercise. In one of the attached reports, hemoglobin and PCV (packed cell volume) is high with increased RB...  Read Full »

What causes increase in the level of hemoglobin?

Query: Hi doctor, My hematology report shows a hemoglobin of 18.8 g/dL, hematocrit of 54.0 % and mean corpuscular hemoglobin concentration of 34.7 g/dL, and red cell distribution width of 19.3 % (all are high). The other parameters such as RBC and WBC are found normal. I have a comment on the morphology o...  Read Full »


Dr. Mubashir Razzaq Khan

Hematologist

Answer: Hi, Welcome to icliniq.com. You have a condition showing an increased level of hemoglobin. Elevated hemoglobin is seen in smokers, in people living at high altitudes, congestive cardiac failure, chronic obstructive pulmonary disease, some erythropoietin secreting adenomas of a kidney, and very rar...  Read Full »

Does the presence of JAK2 gene mutation automatically rule out CML?

Query: Hi doctor, My platelet has always been high in the range of 600 to 700 x 10"9/L. My other blood count is within the normal range as of today. Ten years ago, I had two BCR or ABL test (peripheral blood) to rule out CML; one test came back positive, the other negative. Which test should I believe? Th...  Read Full »


Dr. Parth R Goswami

Family Physician, General Practitioner, Hematologist, Pathologist

Answer: Hello, Welcome to icliniq.com. I can understand your concern. Do not worry. I will try to answer all of your questions. Following is my answers and opinion to your questions. RT PCR (Reverse transcriptase-polymerase chain reaction) is a highly accurate test to check BCR ABL mutation to rule out...  Read Full »

Can hemoglobin and hematocrit be elevated due to testosterone injections?

Query: Hello doctor, I am concerned about my CBC. Three years back, my hematocrit has usually been in 40 (upper range). Last year, my doctor gave me testosterone injections. Five months ago, we found out my hematocrit went to 52.3. I stopped taking the infusion, and four months back, I went to a hematolog...  Read Full »


Dr. Parth R Goswami

Family Physician, General Practitioner, Hematologist, Pathologist

Answer: Hello, Welcome to the icliniq.com. I can understand your concern. Following is my opinion on your asked questions. Initially, four months ago, your hemoglobin and hematocrit are elevated due to testosterone injections. You had secondary polycythemia at that time. Testosterone induced polycythemia...  Read Full »

I have increased RBC along with decreased MCV and MCH. What could be the reason?

Query: Hi doctor, If my complete blood count has high RBC value and low MCV and MCH values, what is the possible diagnosis for me?  Read Full »


Dr. Parth R Goswami

Family Physician, General Practitioner, Hematologist, Pathologist

Answer: Hi, Welcome to icliniq.com. High RBC count is called polycythemia. If it is persistently high, then the cause should be evaluated. Respiratory causes like COPD (chronic obstructive pulmonary disease) and cardiac causes can lead to secondary polycythemia. Primary polycythemia is a myeloproliferative...  Read Full »

Does A Hematocrit Of 49.2 Indicate Polycythemia?

Query: Hello doctor,My Hb is 15.8 but HCT is 49.2 and total RBC count is 5.63. What is the reason? I fear about polycythemia. Is it possible to reduce HCT?  Read Full »


Dr. Abdul Aziz Khan

Hematologist, Medical Oncologist

Answer: Hello, Welcome to icliniq.com. If you are a smoker, then stop smoking. At this stage, secondary polycythemia is more common than primary and smoking is the most common reason for secondary. For further queries consult a hematologist online --> https://www.icliniq.com/ask-a-doctor-online/hemat...  Read Full »

My CBC shows high hemoglobin and hematocrit. Should I be concerned about PV?

Query: Hello doctor, I am a 55-year-old male. Routine CBC report shows hemoglobin 17.1, hematocrit 51.5, and platelets 255 (up from 201 last year). Should I be concerned about PV?   Read Full »


Dr. Parth R Goswami

Family Physician, General Practitioner, Hematologist, Pathologist

Answer: Hello, Welcome to the icliniq.com. In polycythemia vera, hemoglobin level is usually more than 17.5, and hematocrit is more than 55. So you need not concern about polycythemia vera. The chance of secondary polycythemia also seems to be very less. So you need not worry about your CBC (complete bloo...  Read Full »

What can be the reason for elevated RBC, Hb and Hct?

Query: Hi doctor, I am a 34 year old female. I have been itching all over for months and constantly covered with bruises, petechiae and livedo reticularis. I was diagnosed with erythromyalgia. I also have severe bone pain. My blood work came back with elevated RBC, Hb, Hct, low alkaline phosphate, low BUN...  Read Full »


Dr. Prakash H Muddegowda

Geriatrician, Hematologist, Pathologist

Answer: Hi, Welcome to icliniq.com. Based on your query, my opinion is as follows: The elevated hemoglobin, red blood cell count and hematocrit signify polycythemia. Elevated Vitamin B12 level is one of the markers of myeloproliferative disorder. I would strongly think of polycythemia vera. Other valu...  Read Full »

Is polycythemia vera related to cancer?

Query: Hello doctor,I am a female, 50 years old and want to know whether polycythemia vera is related to cancer or not. I have taken JAK2 mutation test which is negative. What is this test for? I have erythromelalgia blood disorder. Is all this connected to cancer? I want to understand this test and doubts...  Read Full »


Dr. Satyajit Jalinder Pawar

Internal Medicine Physician, Medical Oncologist, General Medicine Physician

Answer: Hello, Welcome to icliniq.com. Polycythemia vera is not exactly cancer. It comes under the group of diseases called myeloproliferative disorders. Basically, it is an uncontrolled proliferation of your blood cells. In polycythemia vera, your red blood cells increase in an uncontrolled way. Usually ...  Read Full »

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