Polycythemia Vera

Polycythemia vera is a slowly progressive and rare blood cancer where the bone marrow produces a lot of red blood cells. This excess red blood cells thicken the blood and cause the blood to flow slowly. It can cause blood clots that can result in heart attack and stroke.

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My blood tests show mild splenomegaly. Do I have polycythemia vera?

Query: Hi doctor, I had COVID-19 twice in three months. I have attached my CBC report (attachment removed to protect the patient's identity). The reports showed mild splenomegaly. I am worried the most about polycythemia vera. I just moved to a new city and cannot get a consultation until next year. I ran ...  Read Full »


Dr. Mubashir Razzaq Khan

Answer: Hi, Welcome to icliniq.com. I understand your concern. I have reviewed your reports (attachment removed to protect the patient's identity). Your hemoglobin and hematocrit are borderline high, and liver enzymes are deranged, the blood glucose level is relatively high, the spleen is slightly enlar...  Read Full »

My mother is healthy, but her blood report suggests that her vitamin B12 levels are high. Why?

Query: Hello doctor, My mom is 73 years old and is active for her age. We recently got some tests done for her, some of them are a blood sugar test, liver function test, kidney function test, and lipid profile. All reports turned normal except for the vitamin B12 test, which is higher than normal. Her B12...  Read Full »


Dr. Archana

Answer: Hello, Welcome to icliniq.com. I read your query and understand your concern. Kindly get a peripheral smear for your mother to know if she has megaloblastic anemia. Usually, high levels of vitamin B12 cause polycythemia vera, joint pains, and generalized body pains. If she is having a complete bl...  Read Full »

Does my blood report suggest I have polycythemia vera?

Query: Hi doctor, I would like to know if my complete blood test indicates that I have polycythemia vera. I had a blood test two months back, and my hemoglobin was 17.9 grams per deciliter, RBC 6.06 x 10*12/L, HCT 49.6 percent, and platelet count was 171 × 109/L. Then a month later, I took my blood test i...  Read Full »


Dr. Goswami Parth Rajendragiri

Answer: Hello, Welcome to the icliniq.com. I understand your concern. The EPO (erythropoietin) is within the normal range, so do not worry about that. As your EPO is within the limit chance of polycythemia Vera is very low. Kindly let me know if you have a smoking history, cardiac disease history, or res...  Read Full »

My annual health checkup reports indicate a high RBC count. What does it mean?

Query: Hello doctor, I have attached a report as part of my regular annual check-up. My free RBC (red blood cell) indicators are very high, and when I researched a bit, it pointed to PCV (packed cell volume) and leukemia. I am apprehensive. As a follow-up, I also tested for LDH (Lactate dehydrogenase). It ...  Read Full »


Dr. Goswami Parth Rajendragiri

Answer: Hi, Welcome to icliniq.com. I understand your concern. Following is my opinion of your asked questions. I have seen the attached report (attachments removed to protect the patient's identity). It shows borderline high hemoglobin, high PCV, and RBC mass. So it could be polycythemia. But it does n...  Read Full »

My hemoglobin and hematocrit are high, and I get very anxious about it. What can be the cause?

Query: Hi doctor, I had my annual blood test done. On my CBC, my hemoglobin and hematocrit always come back high at the figures in the photo. Before two years, I had some tests to rule out polycythemia vera. They tested for the JAK2 mutations, which returned normal, as did the leukemia panel. My EPO and LD...  Read Full »


Dr. Mubashir Razzaq Khan

Answer: Hi, Welcome to icliniq.com. I went through your data (attachments removed to protect the patient's identity). Your hemoglobin is at borderline, but your hematocrit is clinically high. Elevated hemoglobin is seen in smokers, people living at high altitudes, congestive cardiac failure, and chronic obs...  Read Full »

I am 25 years old and have had high Hb and RBC levels for the past two years. Can I be affected by polycythemia vera?

Query: Hello doctor, I am a 25-year-old male and have had high hemoglobin and RBC levels for over two years. Recently, I got a hemogram that again shows elevated RBC and Hb levels and hematocrit within normal. So my hematologist asked me for the JAK 2 exon mutation 12 and 14 tests. I am worried that I have...  Read Full »


Dr. Goswami Parth Rajendragiri

Answer: Hi, Welcome to icliniq.com. Your Hb (hemoglobin), hematocrit, and RBC (red blood cells) are high. The diagnosis is either primary polycythemia vera or secondary polycythemia. I require your total WBC (white blood cell) count and platelet to comment further. You can attach your reports; if you have...  Read Full »

Will dehydration and smoking cause changes in CBC report?

Query: Hello doctor, I am a 27-year-old male. I have had dizziness, weakness and shaking, sometimes chest pain, and shortness of breath. I have stiff upper back pain, and most of my body clicks and pops when I move. I have also had a loss of appetite, like no appetite at all and weight loss. I had bad upp...  Read Full »


Dr. Goswami Parth Rajendragiri

Answer: Hello, Welcome to icliniq.com. In the attached report (attachment removed to protect patient identity), cholesterol level is high. For that, take a low-fat diet and do some morning exercise. In one of the attached reports, hemoglobin and PCV (packed cell volume) is high with increased RBC (red bl...  Read Full »

Why is Aspirin advised for high RBC and hemoglobin count?

Query: Hi doctor, I am a 40 year old male. My hemoglobin was 18.3 g/dL, but it has come down to 17.7 g/dL since the last two months. My RBC count varies between 6.1 to 6.27 now, and PCV is 51.9 %. I am taking mini Aspirin as suggested by my doctor. Do I have any reason to worry?  Read Full »


Dr. Goswami Parth Rajendragiri

Answer: Hi, Welcome to icliniq.com. Your hemoglobin level, RBC (red blood cells), and PCV (packed cell volume) are high. The lymph node, liver, and spleen need to be clinically examined. Do you have a history of dizziness, weakness, and stroke? High level of RBC and hemoglobin can cause blood clots and can ...  Read Full »

My 22-year-old son has elevated RBC, Hgb, and HCT and is a smoker. Does he have polycythemia vera?

Query: Hello doctor, My son is 22 years old. His routine physical examination and complete blood count showed elevated RBC, Hgb, and HCT. Hgb was 18, HCT was 59, and normal platelets. Additionally, he had JAK2-negative, exons normal, normal serum EPO, normal B12, normal electrophoresis, and an ultrasound o...  Read Full »


Dr. Goswami Parth Rajendragiri

Answer: Hello, Welcome to icliniq.com. Thank you for your query. According to the blood result, we have to rule out polycythemia vera. His EPO (erythropoietin) is normal with no hepatosplenomegaly in USG (ultrasonogram) scan. Moreover, JAK2 and exon marker investigations are negative. So polycythemia ver...  Read Full »

I have been having bone pain, nausea, headache, and tiredness for a few months, and my blood test showed high RBC, hemoglobin, hematocrit, and MCHC values. Does it indicate polycythemia vera?

Query: Hello doctor, I recently got my blood work done because of my symptoms. I have been feeling tired and having bone pain, nausea, and headaches. However, when I got my blood work back on the hematology section, my RBC, hemoglobin, hematocrit, and MCHC all came back abnormally high. Is this something I...  Read Full »


Dr. Goswami Parth Rajendragiri

Answer: Hello, Welcome to icliniq.com. I read your query and can understand your concern. I have checked your report (attachment removed to protect the patient's identity). It also shows high levels of RBC (red blood cells), hematocrit and hemoglobin levels. So your diagnosis is polycythemia. But it can ...  Read Full »

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