Dopamine is a neurotransmitter that is found naturally in the human body. It helps in sending signals from the body to the brain. The levels of dopamine influence function like mood, sleep, memory, concentration, and learning.

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I have horrible depression and tried many treatments. Can Dopamine agonists help with depression when other things fail?

Query: Hello doctor, I have ongoing horrible depression, I have tried TMS, every SSRI, Ketamin, and electroshock. I take Ritilin, Colonpin, Levothyroxine, and Ambien. Would a dopamine agonist possibly help with depression when all others have failed? Please suggest.  Read Full »

Dr. Aditya Gupta

Answer: Hello, Welcome to It is a refractory depression. There are a few pieces of evidence to show that dopamine agonists like Pramipexole may help in such cases. 1. Adding Bupropion (Ethyl cellulose aqueous dispersion (NF), glyceryl behenate, methacrylic acid copolymer) to SSRI (selective ...  Read Full »

My dopamine receptors have been desensitized due to excessive internet use. Please help.

Query: Hello doctor, I have been a bit stumped because of perhaps being misguided by my research online; hence I thought to ask a doctor about it, not to play a dice roll on my health. I have been tackling and battling depression for a long time. My symptoms have been drastically altered after taking selec...  Read Full »

Dr. Abhishek Juneja

Answer: Hi Welcome to I appreciate your interest in the pathogenesis and mechanisms of how these medicines work and their long-term implications. I advise you to limit your internet search as things are way more complex than they appear. It is worthwhile to continue taking the antidepressants...  Read Full »

I have spastic paraplegia.Will dopamine help me?

Query: Hello doctor, I have spastic paraplegia. Everything I have tried has not worked. I was told to try a medication called L-Dopa. Will this medication help me?  Read Full »

Dr. Anshul Varshney

Answer: Hi, Welcome to L- Dopa is Levodopa and is a drug for parkinson's disease. It will help you in spastic paraplegia in case there is a deficiency of dopamine in substantia niagra of your brain. It is definitely going to help you if there is any deficiency. But if there is no deficiency, ...  Read Full »

I have stage 4 liver cirrhosis and my BP is 99/68 mmHg. Is this normal?

Query: Hello doctor,Is a BP of 99/68 good in case of stage-4 cirrhosis and liver failure? I am currently on Dopamine, Potassium chloride and Albumin human 25.  Read Full »

Dr. Sagar Ramesh Makode

Answer: Hello, Welcome to You have mentioned that you are on Dopamine, which is a medicine to increase the BP (blood pressure). So, if we decrease the dosage of Dopamine, the BP may fall. Also, whether the BP is good or not depends on the functioning of other organs like whether there is urine ...  Read Full »

How do I overcome porn addiction?

Query: Hello doctor, I am watching porn videos for the past two years. I used to watch it once in a week and now it has become addiction. My mind wants to see it. I masturbate along watching porn videos. My reading concentration is now weak . I want to get rid of watching porn videos . Friends also watch, ...  Read Full »

Dr. Saraswat Kumarshri Shriniwas

Answer: Hello, Welcome to After going though your history, it is apparent that you are suffering from porn addiction. To overcome this, you can follow some techniques. Any addiction gives pleasure by increasing dopamine levels in the pleasure centers of your brain. You need to find some healt...  Read Full »

Does hormonal imbalance cause difficulty to conceive?

Query: Hi doctor, I was diagnosed with PCOS and my insulin and prolactin levels are 30.9 and 60 respectively. My doctor put me on Glucophage and Prolactin for these before two months. I got my periods on the same month. But, until now no signs of periods. I have mild thigh pain, heaviness in my stomach, li...  Read Full »

Dr. Sameer Kumar

Answer: Hello, Welcome to Your insulin and prolactin levels are high and you have been rightly started on Glucophage (Metformin) and a dopamine agonist. This will help bring down the levels over the next two to three weeks and shall help balance your hormones. If the menses are missing for more...  Read Full »

Which is the medication recommended for early parkinson's disease?

Query: Hello doctor, I was diagnosed with parkinson last year at the age of 45. I am on Azilect since then. My symptoms are mild, stiffness, lately I did not sleep well and I suffer from RLS about 4-5 nights per week. I do sport but everything which required quick movement, I am not able to do it well. My...  Read Full »

Dr. Aida Abaz Quka

Answer: Hello, Welcome to I read carefully your question and would explain that in the early stages of Parkinson's disease, in young persons, it is recommendable to start treatment with IMAO (which you are already taking, Azilect) and a dopamine agonist. In the this regard, both Neuropro a...  Read Full »

How does an award impact one's career?

Query: Hi doctor, I am seeking insight from a psychological professional on how awards affect us. Why we give them? Why we deny them to others? And what impact it causes to the one who is receiving them or not has on one's career? Please explain both from the recipient or non-recipient perspective and fro...  Read Full »

Dr. Seikhoo Bishnoi

Answer: Hello, Welcome to The topic of effects of awards is complex. The awards act as positive reinforcement to any individual and thus the probability of repetition of behavior increases. If we consider it from a psychological point, then if an individual is given award then it acts as an ...  Read Full »

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