Consanguineous marriage indicates union between couples who are close relatives or cousins. They are genetically related and descended from common ancestors. They cause consanguineous transmissions. The consanguineous union's offsprings have an increased risk of genetic disorders as the expression of an autosomal recessive gene is inherited from their common ancestor.
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I got married to my relative, having the same blood group. Do I need to worry about my second baby?
Query: Hi doctor,I got married to my relative and we have the same blood group. My first baby is quite healthy and fine without any problems. Now, we are planning for a second baby. We did not check about the Rh factor yet and we are afraid that any problem might come in the second pregnancy. Should I worr... Read Full »
Answer: Hi, Welcome to icliniq.com. You and your husband are relatives, so in such a situation, prenatal or preconception counseling is beneficial to avoid the consanguineous disease transmission mainly autosomal recessive problems like thalassemia. If your blood group is Rh negative and if the fetus is... Read Full »
I married my cousin. What are the chances we may deliver a baby with Down's syndrome?
Query: Hello doctor,I am a 31-year-old female. I married my cousin and now I am pregnant. We are healthy and do not have any systemic disorders. What are the chances we may deliver a baby with Down’s syndrome? Is Down's syndrome more common in children born to consanguineous couples? Can it be diagnosed... Read Full »
Answer: Hello, Welcome to icliniq.com. I have gone through your case, and I understand your concern. Yes, there are more chances of anomalies like Down's syndrome in consanguineous marriage. It can be detected quickly in antenatal periods only. How many weeks are you pregnant? At 11 to 14 weeks you should ... Read Full »
Can I marry someone of the same blood group?
Query: Hi doctor, I am going to get married after six months. My fiance is my dad's sister's son. Our blood groups are the same B+. Will there be any problem to the baby? If yes, then what is the solution? Read Full »
Answer: Hi, Welcome to icliniq.com. The blood group will not be a problem but, there are chances of high consanguinity. Consanguineous marriages are associated with an increased risk for congenital malformations and autosomal recessive diseases, with some resultant increased postnatal mortality in the offsp... Read Full »
My wife gave birth to a dead baby. Has it occurred as we are cousins?
Query: Hi doctor, I am married to my cousin, and she is my blood relative. My blood group is B positive, and my wife's is A positive. She gave birth to a dead baby, and it was her first pregnancy. I am deeply concerned if this is because of our relationship. Please guide me. Read Full »
Answer: Hi, Welcome to icliniq.com. In consanguineous marriage, the chance of spread of autosomal recessive disorder and certain congenital malformations is present. Hence, both of your CBC (complete blood count) report and HPLC (high-performance liquid chromatography) should be done to rule out hemoglobi... Read Full »
Can I have a normal child on marrying a girl with a family history of genetic abnormalities?
Query: Hi doctor, I am planning to get married. My father got married to his elder sister's daughter, and my younger brother had cerebral palsy at birth. My sister has a low IQ, but she is manageable. In my fiance's family, her paternal grandfather is married to his sister's daughter. They have a daughter... Read Full »
Answer: Hello, Welcome to icliniq.com. Cerebral palsy and a low intelligence quotient in your siblings need in-depth analysis. Both of these problems happening to consanguineous parents cannot be taken as incidental or independent of each other. The deafness on your fiance's side needs genetic evaluation ... Read Full »
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