Benign tumors of the prolactin-producing pituitary gland or prolactinoma develop independently without any known cause, although multiple endocrine neoplasia type 1 inherited disorder is thought to increase the risk of developing pituitary tumor. There are increased circulating prolactin levels. In children, it prevents puberty during their growth. In adults, it causes osteoporosis, infertility, loss of sexual desire, vaginal dryness, galactorrhea, erectile dysfunction, and menstrual problems. Dopamine agonists usage is advocated for its treatment. Surgery and radiation are necessitated in the advanced stages.

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I have high prolactin.Will this affect my fertility?

Query: Hi, My doctor said that I have high prolactin, almost 200, but I have regular periods. My periods are regular and usually have an interval of 30-33 days. I do not have any othe menstrual symptoms, other than milky nipple discharge. I take ovulation tests every month and comes back positive on my fer...  Read Full »

Dr. Sameer Kumar

Answer: Hello, Welcome to High prolactin levels with galactorrhea (milky nipple discharge other than normal breast feeding) can often cause delayed ovulation and irregular menses. The ovulation kits detect the LH surge and do not exactly tell us if there has been ovulation at all. Th...  Read Full »

Is it possible for an otherwise healthy person to have gynecomastia?

Query: Hello doctor, I had prolactinoma diagnosed with secondary hypogonadism. I was treated with cabergoline and hydrocortisone for a few years and then taken off hydrocortisone when the adrenals began to function properly. My most recent blood tests came back normal, and I was tested for loads of other...  Read Full »

Dr. Sumit Srivastava

Answer: Hello, Welcome to Gynecomastia could be due to a testosterone deficiency, thyroid disorder or adrenal insufficiency in your case. Since your prolactin levels are normal and there is no further growth, it is no longer due to the prolactinoma. I would suggest you have your seru...  Read Full »

May I know if medicine help in treating adenoma?

Query: Hello doctor, I am 29 years old female. My prolactin levels were found to be 1000 ng/ml. Pituitary size on MRI showed 17 × 26 × 15 mm. The endocrinologist said it is macroadenoma and asked to consult a neurosurgeon. My query is that whether the pituitary size is too big. Can an endocrin...  Read Full »

Dr. Mahmoud Ahmed Abdelrahman Abouibrahim

Answer: Hi, Welcome to I understand all your concerns. From what you have mentioned, you have a large prolactinoma which requires treatment. Usually, we start with medication in order to reduce the hormone level as well as the mass size. In those with macroadenoma, surgery is usually require...  Read Full »

Will a prolactinoma shrink for a patient in his 70s after increasing the dose of Cabergoline?

Query: Hello doctor, I would appreciate your opinion about a case in which pituitary surgery has been indicated. A patient in his early 70s was diagnosed with a prolactinoma ten years ago. He was prescribed a tablet of Dostinex 0.5 mg per week, which was then reduced to 0.5 mg per two weeks. The prolactin ...  Read Full »

Dr. Shaikh Sadaf

Answer: Hello, Welcome to Pituitary surgery is rarely required in prolactinomas and is generally reserved for patients intolerant or resistant to Dopamine agonist therapy, Cabergoline. Surgery is indicated only if visual field defects, headaches, and hypopituitarism are present. In addition, the...  Read Full »

Why do I have high prolactin and low testosterone levels in the body?

Query: Hello doctor, My doctor wants me to get an MRI after my blood work. I wanted to get a second opinion, and I have attached my blood results. My prolactin is 20.4 (above normal), total testosterone is 269.3 (below normal), free testosterone is 8.9 (normal), FSH is 3.7 (normal), LH is 2.9 (normal). I ...  Read Full »

Dr. Divakara. P

Answer: Hi, Welcome to Thanks for posting your query. See, your prolactin levels are high. There are only two reasons for that: Problems in the testes. Problems in the pituitary gland located in the brain. Now your endocrinologist wants to know if there is any pituitary problem, which is causin...  Read Full »

Will high prolactin levels lead to prolactinoma?

Query: Hello doctor, I am 40 years old. I have irregular for the past six months. I got checked my prolactin as per doctor advise which came out to be 27. Then the doctor prescribed me Estrogen-progesterone. Then the cycle was still irregular. After that my prolactin rise to 38. Cabergoline was prescribed...  Read Full »

Dr. Shaikh Sadaf

Answer: Hello, Welcome to I just read your query and from what you have mentioned it appears that you had slight high prolactin levels and you took Cabergoline to treat that. Well, if at all you had some pituitary problem it gets resolved with Cabergoline and unless you do not have the same p...  Read Full »

Why am I having high prolactin level?

Query: Hi doctor, I would like help in understanding my situation and a second opinion to that of my GP. I had a blood test two months back which showed serum prolactin levels at 618. I was unaware what the test was for so breastfed before and during the blood being taken. I breastfeed a toddler betwe...  Read Full »

Dr. Syed Abdul Kader

Answer: Hi, Welcome to To get rid you of your worries, I should let you know the usual level of prolactin in different conditions. The upper limit of normal for many assays of serum prolactin is approximately 500 mIU/L (24 ng/mL). In non-pregnant and non-lactating patients, monomeric prolacti...  Read Full »

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