Benign tumors of the prolactin-producing pituitary gland or prolactinoma develop independently without any known cause, although multiple endocrine neoplasia type 1 inherited disorder is thought to increase the risk of developing pituitary tumor. There are increased circulating prolactin levels. In children, it prevents puberty during their growth. In adults, it causes osteoporosis, infertility, loss of sexual desire, vaginal dryness, galactorrhea, erectile dysfunction, and menstrual problems. Dopamine agonists usage is advocated for its treatment. Surgery and radiation are necessitated in the advanced stages.
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Query: Hello doctor, I am 40 years old. I have irregular for the past six months. I got checked my prolactin as per doctor advise which came out to be 27. Then the doctor prescribed me Estrogen-progesterone. Then the cycle was still irregular. After that my prolactin rise to 38. Cabergoline was prescribed... Read Full »
Answer: Hello, Welcome to icliniq.com. I just read your query and from what you have mentioned it appears that you had slight high prolactin levels and you took Cabergoline to treat that. Well, if at all you had some pituitary problem it gets resolved with Cabergoline and unless you do not have the same p... Read Full »
Query: Hi doctor, I would like help in understanding my situation and a second opinion to that of my GP. I had a blood test two months back which showed serum prolactin levels at 618. I was unaware what the test was for so breastfed before and during the blood being taken. I breastfeed a toddler betwe... Read Full »
Answer: Hi, Welcome to icliniq.com. To get rid you of your worries, I should let you know the usual level of prolactin in different conditions. The upper limit of normal for many assays of serum prolactin is approximately 24 ng/mL. In non-pregnant and non-lactating patients, monomeric prolactin concentrat... Read Full »
Query: Hi, My doctor said that I have high prolactin, almost 200, but I have regular periods. My periods are regular and usually have an interval of 30-33 days. I do not have any othe menstrual symptoms, other than milky nipple discharge. I take ovulation tests every month and comes back positive on my fer... Read Full »
Answer: Hello, Welcome to icliniq.com. High prolactin levels with galactorrhea (milky nipple discharge other than normal breast feeding) can often cause delayed ovulation and irregular menses. The ovulation kits detect the LH surge and do not exactly tell us if there has been ovulation at all. Ther... Read Full »
Query: Hello doctor, I had prolactinoma diagnosed with secondary hypogonadism. I was treated with cabergoline and hydrocortisone for a few years and then taken off hydrocortisone when the adrenals began to function properly. My most recent blood tests came back normal, and I was tested for loads of other... Read Full »
Answer: Hello, Welcome to icliniq.com. Gynecomastia could be due to a testosterone deficiency, thyroid disorder or adrenal insufficiency in your case. Since your prolactin levels are normal and there is no further growth, it is no longer due to the prolactinoma. I would suggest you have yo... Read Full »
Query: Hello doctor, I am 29 years old female. My prolactin levels were found to be 1000 ng/ml. Pituitary size on MRI showed 17 × 26 × 15 mm. The endocrinologist said it is macroadenoma and asked to consult a neurosurgeon. My query is that whether the pituitary size is too big. Can an endocrin... Read Full »
Answer: Hi, Welcome to icliniq.com. I understand all your concerns. From what you have mentioned, you have a large prolactinoma which requires treatment. Usually, we start with medication in order to reduce the hormone level as well as the mass size. In those with macroadenoma, surgery is usually require... Read Full »
Query: Hello doctor, I would appreciate your opinion about a case in which pituitary surgery has been indicated. A patient in his early 70s was diagnosed with a prolactinoma ten years ago. He was prescribed a tablet of Dostinex 0.5 mg per week, which was then reduced to 0.5 mg per two weeks. The prolactin ... Read Full »
Answer: Hello, Welcome to icliniq.com Pituitary surgery is rarely required in prolactinomas and is generally reserved for patients intolerant or resistant to Dopamine agonist therapy, Cabergoline. Surgery is indicated only if visual field defects, headaches, and hypopituitarism are present. In addition, the... Read Full »