Total Iron Binding Capacity

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My iron saturation percentage is higher than normal. Does it mean I have hemochromatosis?

Query: Hi doctor, I am a 52-year-old male (5 foot 7 inches, 157 pounds) with no symptoms. I had some routine annual lab tests performed three months back, I had an elevated Ferritin level of 325.9 (normal is 40 to 250 ng/mL). So I had more comprehensive lab tests done last week. Please see attached lab re...  Read Full »


Dr. Mian Shah Yousaf

Answer: Hello, Welcome to icliniq.com. I reviewed all your tests (attachments removed to protect the patient's identity). Your serum transferrin saturation suggests hemochromatosis, but it is an initial screening test, and your ferritin is not that high. Your liver enzymes are also normal, so there is nothi...  Read Full »

Can serum iron levels increase from taking iron supplements?

Query: Hi doctor, I am 44-years-old female. I am a vegetarian. My current medications are fish oil, multivitamin, vitamin C supplements, and a high dose of vitamin B for my neuropathy. I drink beer or wine two servings three times a week. I have an increased iron value with no other symptoms. I consulte...  Read Full »


Dr. Abdul Aziz Khan

Answer: Hi,Welcome to icliniq.com.I agree with your doctor that iron supplementation may cause high serum iron since you have normal ferritin and hemoglobin. So, I suggest stopping iron and repeat CBC (complete blood count), iron, and ferritin after three months. And kindly upload your reports for review.Th...  Read Full »

I have increased RBC along with decreased MCV and MCH. What could be the reason?

Query: Hi doctor, If my complete blood count has high RBC value and low MCV and MCH values, what is the possible diagnosis for me?  Read Full »


Dr. Parth R Goswami

Answer: Hi, Welcome to icliniq.com. High RBC count is called polycythemia. If it is persistently high, then the cause should be evaluated. Respiratory causes like COPD (chronic obstructive pulmonary disease) and cardiac causes can lead to secondary polycythemia. Primary polycythemia is a myeloproliferative...  Read Full »

Will increased iron saturation cause damage of internal organs?

Query: Hello doctor, I am 20 years old. Today I got lab results that show my iron saturation is 73% and my iron serum is 278 ug/dl. I am 6 feet tall and have lost weight down to 127 pounds. I have joint pain, headaches, digestive issues, low appetite, and depression. My mom got me an appointment with a h...  Read Full »


Dr. Parth R Goswami

Answer: Hi, Welcome to icliniq.com. Your serum iron level is high. So we have to rule out iron over storage means hemochromatosis like picture. For that, serum ferritin and transferrin saturation have to be done. Your serum ferritin level is normal, So iron storage seems less likely. However, investigate...  Read Full »

Can iron deficiency cause tremors?

Query: Hi doctor, I am just wondering if it is possible to have neurological symptoms with low ferritin levels. My hemoglobin is 13, but the last check on ferritin said it was 5.3. I am suffering severe internal tremors, fatigue, cold hands and feet and weak shaking legs. My symptoms improve while on a s...  Read Full »


Dr. Singh Smrita

Answer: Hello, Welcome to icliniq.com. A low ferritin can cause fatigue and weakness. A full iron deficiency panel needs to be done. This includes: CBC (complete blood count) Differentials. Hemoglobin. RBC (Red blood cell). Hematocrit. RDW-CV. MCV. MCH. Serum iron. TIBC (total iron binding capacity). Satura...  Read Full »

Are low values of UIBC and DHEA the reason for chronic fatigue?

Query: Hello doctor, I am a 47-year-old male. I have chronic fatigue being on healthy diet. I am not on any medication. There is also low libido. In the blood test report, the levels of UIBC, DHEA, estradiol, vitamin D, progesterone, phosphorus, and platelets were low from the normal level and high B1...  Read Full »


Dr. Divakara P

Answer: Hello, Welcome to icliniq.com. Your chronic fatigue can be explained by low levels of vitamin D, low phosphorus, and low DHEA (dehydroepiandrosterone). I will explain why do you have these low levels. There are many causes of vitamin D deficiency, but most common is inadequate exposure to sunlight...  Read Full »

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