Q. My father has side effects with Amlodipine and Lasilactone. Please suggest some other medicine.

Hello,

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No, Lasilactone is not necessary now, and it should be avoided considering his history of getting unconscious with it. We should slightly increase the dose of his current medications. However, Amlodipine should be changed to Cilnidipine as the leg and feet swelling is likely related to Amlodipine. He should sleep with legs elevated. The 2.5 mg of Amlodipine is equivalent to 5 mg of Cilnidipine. Since he is experiencing intermittent high BP (blood pressure) readings, we should increase the antihypertensive dose. He should have tablet Cilnidipine 10 mg in the morning and 5 mg in the evening (equivalent to 5 mg Amlodipine in the morning and 2.5 mg in the evening). You can increase the dose to 10 mg twice daily if baseline BP remains elevated, and maybe reduce to 5 mg twice daily if BP goes down. Make a chart of blood pressure readings three times a day readings. Now you may continue to give Sorbitrate intermittently if necessary or may give an additional 5 mg dose of Cilnidipine if necessary (if receiving 15 mg in the day, the maximum dose is 20 mg). Later if this does not work for him, then medications may be changed to Telmisartan if his creatinine is normal. You may keep Telmisartan 20 mg with you for emergency purposes and be given if BP goes high despite other medications (check his creatinine level in his blood reports before providing this). You can also give antianxiety medications during anxiety episodes like Clonazepam, which would subside anxiety and lower BP. I hope this helps you and get back if you have any doubts.

Hi,

Welcome back to icliniq.com.

He should have plain Cilnidipine, not with Atenolol or other beta-blockers. Cilnidipine and Amlodipine are similar medications, with Cilnidipine having less side effects like leg swelling than Amlodipine. Cilnidipine dose adjustment may take a while as the body reacts differently to each molecule. All the best.