Cancer of the lymphatic system, which comprises of lymph nodes and vessels that carry lymph fluid throughout the body, is called lymphoma. It can affect either the bone marrow, thymus, spleen, tonsils, or the lymph nodes. Here, the lymph nodes become swollen and tender.

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Do all pleural effusions need pleurodesis?

Query: Hi doctor, The patient is a 52 years old female. 25 days ago, core biopsy of retroperitoneal lymph node non-Hodgkin's mature B cell lymphoma diffusely positive for CD10, CD20, BCL6 and BCL12. Bone marrow biopsy showed erythroid hyperplasia with focal micronormoblastic maturation. She is suffering wi...  Read Full »

Dr. Bharat Patodiya

Family Physician, General Medicine Physician, General Practitioner, Internal Medicine Physician, Medical Oncologist

Answer: Hello, Welcome to Thank you very much for being specific in what you want to ask. For lymphoma associated effusion, we do not suggest pleurodesis (procedure to remove excess fluid in pleural space) as most of the patient responds to chemotherapy. One cycle is a short time to know if the...  Read Full »

Please explain the cause and treatment for hypopigmented mycosis fungoides.

Query: A girl age 9 yrs report shows. Biopsy shows sparse superficial perivascular infiltrate of Lymphocytes. The epidermis shows slight psoriasiform hyperplasia and infiltration by numerous small and large Lymphocytes without much spongiosis. Several Lymphocytes are aligned along the basal layer in toy ...  Read Full »

Dr. Charu Bansal

Dermatologist, Cosmetologist

Answer: Hello, Mycosis fungoides is a type of cutaneous T cell lymphoma meaning abnormal proliferation of T cells in our skin. As such, there is no well definite cause. Its caused by an interplay of various factors, There is abberations in chromosomes triggerred by a persistent antigen which can be an in...  Read Full »

Can you please explain my father's test results?

Query: Hi doctor, My father is 78 years old. He generally maintains good health except being diabetic for the last two years. However, since last once month his WBC, urea and creatinine values are abnormally high indicating kidney malfunctioning. He has lost 4 to 6 kg in the last three months and his appe...  Read Full »

Dr. Prakash H Muddegowda

Geriatrician, Hematologist, Pathologist

Answer: Hi, Welcome to Based on your query and attached reports (attachment removed to protect patient identity), my opinion is as follows: Diabetes appears to be in good control. However, due to renal disease, blood pressure must be high. He is on multiple medications for blood pressure for no...  Read Full »

Do I have leukemia?

Query: Hi doctor, My blood test shows lymphocytes 60% where the normal range is 20% to 45%. I had immunophenotyping and the values are CD23 - 2.11%, CD19 - 0.30% and CD5 - 79.9%. What does it indicate? Am I a leukemia patient? Please advise.  Read Full »

Dr. Sadaf Mustafa

General Medicine Physician, Internal Medicine Physician

Answer: Hello, Welcome to I would also like to know the total leukocyte count, platelets, RBC (red blood cell) count. Did you have ESR (erythrocyte sedimentation rate)? Is this the only CBC (complete blood count) you ever had? Is there any fever, chills or weight loss? Please answer these quest...  Read Full »

Is FNB or biopsy needed to check lymph node enlargement?

Query: Hi doctor, I am a 32 year old male. My height is 6 feet and weight is 145 lbs. I am facing a significant unexplained weight loss of more than 45 lbs in four months. My normal weight since high school is 185 to 180 lbs. I am having episodes of significant and frequent drenching night sweats. Also, I ...  Read Full »

Dr. Prakash H Muddegowda

Geriatrician, Hematologist, Pathologist

Answer: Hi, Welcome to Based on your query and attached images (attachment removed to protect patient identity), my opinion is as follows: In view of the clinical symptoms, images could be more of neoplastic etiology. Clearly, with the family history and prominent nodes along with classical his...  Read Full »

What does symptoms like chronic swollen nodes with high CPR and eosinophils signify?

Query: Hello doctor, I am writing to you about my partner. She has had swollen lymph nodes for the past two years. Only other symptoms are high CPR and very slightly higher eosinophils. She had an ultrasound of her right side of the neck today, and I would like to know if you can see anything unusual. Al...  Read Full »

Dr. Ismail Kabakus


Answer: Hi, Welcome to Let me start with the right neck lymph nodes seen on the images (attachment removed to protect patient identity). They have a fusiform shape which is a good sign. They are mildly enlarged, the index one short axis measures 6 mm. Image 1: Lymph node with Doppler box, sh...  Read Full »

Can lymphoma spread to elbow?

Query: Hi doctor, I have just finished three rounds of R-CHOP for stage 1A diffuse large B-cell lymphoma and currently receiving radiation to my hip or groin. Recently I found another lump on my elbow bone, not inside crease but outside. Two weeks ago, my elbow was red and sore. Possibly bursitis but can ...  Read Full »

Dr. Satyajit Jalinder Pawar

Internal Medicine Physician, Medical Oncologist, General Medicine Physician

Answer: Hello, Welcome to As per your history, you had stage 1A DLBCL (diffuse large B-cell lymphoma) and have already completed 3 R-CHOP. On radiation currently, which is standard therapy. Regarding the lump, I would like to know since when it is present, do you have any pain or tenderness,...  Read Full »

Kindly explain my ultrasound report of suspected lymphoma.

Query: Hello doctor, I had a CT scan done for suspected lymphoma because of high CRP, ESR, WBC, night sweats, and intermittent fever. It was found that there was a mass next to my trachea apart from the thyroid gland and they recommended that I have an ultrasound. Can you please review my ultrasound?  Read Full »

Dr. Ruchi Bahuguna

Radiodiagnosis Physician, Radiologist

Answer: Hi, Welcome to I have reviewed the ultrasound images of neck provided by you (attachment removed to protect patient identity). There is a well defined hypoechoic nodule of size 1.8x1.4x0.6cm in left lateral neck with preserved central hilum- highly likely to be an enlarged cervical ...  Read Full »

Does lump in the right anterior triangle of neck suggest lymphoma?

Query: Hello doctor, I am a 21-year-old female. I have a lump in my neck for about nine weeks now. It is between my hyoid bone and sternocleidomastoid muscle on the right anterior triangle of my neck. It is palpable when I tilt my head back. It is probably as big as a penny but not as round as a penny. It...  Read Full »

Dr. Bharat Patodiya

Family Physician, General Medicine Physician, General Practitioner, Internal Medicine Physician, Medical Oncologist

Answer: Hello, Welcome to I understand your concern regarding this lump. I also understand that you have gone through the internet trying to get an approximate diagnosis for the same. As per your history and description, it appears that this lump is arising from superficial structures of th...  Read Full »

Does increase in lmphocyte count indicate leukemia or lymphoma?

Query: Hello doctor, I had a viral infection before two months with fever for five days and cough and increased mucus production for more than two weeks. On a follow-up visit with a PCP, I was given antibiotics for five days Azithromycin and antihistamine Levocetirizine to make sure there is no secondary i...  Read Full »

Dr. Parth R Goswami

Family Physician, General Practitioner, Hematologist, Pathologist

Answer: Hello, Welcome to I have seen your attached report. (attachment removed to protect patient identity). The lymphocytes are slightly elevated. The lymphocytosis seems most likely to be due to previous viral infection of the upper respiratory tract. The peripheral smear report not sho...  Read Full »

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