Nonalcholic Steatohepatitis

Non-alcoholic steatohepatitis is a condition presenting with liver inflammation and damage due to the build-up of fat. It is often caused due to obesity and insulin resistance. It is also caused due to high cholesterol, high triglycerides, polycystic ovarian disease, and an underactive thyroid. The symptoms are fluid accumulation in the abdomen, loss of appetite, nausea, swelling in the legs, and yellowish discoloration of the eyes and skin. In severe cases, it causes scarring of the liver and cirrhosis. It is managed by losing weight and by following a healthy diet. Lowering the levels of cholesterol and triglycerides in the body too helps a lot.

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What does steatohepatitis with perisinusoidal and periorbital fibrosis indicate?

Query: Hello doctor, Please interpret the liver biopsy report shown below. Kindly explain the what stage of fibrosis and confirm whether cirrhosis is present or not. Pathological diagnosis: A. Liver parenchyma biopsy: Steatohepatitis with perisinusoidal and periportal fibrosis. Note: The biopsy ...  Read Full »


Dr. Ujjal Kanti Ray

Answer: Hello, Welcome to icliniq.com. The most common cause of periportal and perisinusoidal fibrosis with chronic inflammatory cell infiltration is due to steatohepatitis in both alcoholic and non-alcoholic. However, chances are very high in alcoholics. Periportal fibrosis can occur due to Schistosoma ...  Read Full »

Can increased cholesterol levels be the reason for my fatty liver?

Query: Hello doctor, I am a 32-year-old male. My height is 5.6 feet and weighs about 90 kg. I have fatty liver and high cholesterol- 166, and LDL - 223. I wanted to ask is this cholesterol because of fatty liver? And is there any supplement that I can take for the liver?  Read Full »


Dr. Ajeet Kumar Lohana

Answer: Hello, Welcome to icliniq.com. Well, the fatty liver and high cholesterol are both different problems. However, both can simultaneously occur at one time and affect each other in different ways. It seems the main problem you have is weight. High cholesterol and fatty liver disease are possibly due ...  Read Full »

Kindly help me interpret my liver USG report.

Query: Hello doctor, Four months before, I was diagnosed with fatty liver, slightly elevated fasting sugar and the level of total cholesterol. My current medications are tablet Viboliv 500 daily two times in a restricted diet and Nexpro RD. I had consumed spicy foods rarely. In the last four months, I l...  Read Full »


Dr. Sadaf Mustafa

Answer: Hello, Welcome to icliniq.com. The fatty liver disease is also known as NASH (nonalcoholic steatohepatitis), which may progress to NAFLD that is nonalcoholic fatty liver disease. The real issue here is to know if you are developing fibrosis or cirrhosis from it. And that is whether you are compens...  Read Full »

Please help me interpret my reports.

Query: Hello doctor, I am a 23 year old female. I am bulimic for the past nine years and also suffering from anxiety and depression for the past five years. I like to drink alcohol a lot. I recently had a checkup and I have attached my test reports for your reference. I am just taking vitamin supplements...  Read Full »


Dr. Sadaf Mustafa

Answer: Hi, Welcome to icliniq.com. Looking into your laboratory reports (attachment removed to protect patient identity), it appears that you are having hepatitis. It could be alcohol induced, viral or a combination of both. The ultrasound will guide to rule out lesions in the liver. It will also help us t...  Read Full »

Is it fine to take Prednisone and Azathioprine for autoimmune hepatitis?

Query: Hi doctor, I have been itching throughout my body, especially after eating, for about two years. I noticed fatigue and shortness of breath about 18 months ago. I stopped smoking before seven years. I stopped drinking before a year as my upper abdominal area started paining after drinking. Before fi...  Read Full »


Dr. Sadaf Mustafa

Answer: Hi, Welcome to icliniq.com. There are a few important facts I would want you to consider. We have to rule out other forms of hepatitis like viral hepatitis, amyloid or iron deposition, NASH (nonalcoholic steatohepatitis) and alcoholic liver disease. All three markers are non-specific; ant...  Read Full »

Can you suggest a low dose of something to help with my severe itching complaint?

Query: Hi doctor, My thyroid levels indicate that I have hyperthyroidism and I am so itchy. Itch is my number one complaint. I also have an elevated heart rate, abnormal liver tests, and weight loss. I made an appointment with an endocrinologist. However, I need help now. I am so itchy. Is there a low dos...  Read Full »


Dr. Shaikh Sadaf

Answer: Hi, Welcome to icliniq.com. Yes, please attach your liver function tests for review.  Read Full »

What is wrong in my annual health checkup report?

Query: Hi doctor, I am a 31 year old male. Recently, I have gone for an annual health checkup. Following are the areas which are highlighted as abnormal for which I seek consultation in evaluating it better. I would like to find the root cause for the same along with medication or lifestyle changes, if a...  Read Full »


Dr. Sadaf Mustafa

Answer: Hello, Welcome to icliniq.com. For eosinophilia, the most important point is to detect and eliminate allergies and worms if you have symptoms of itchy nose, sneezing, wheezing or breathing issues, rash or abdominal pain. Please let me know if you have any one of these. For low Vitamin D, I suggest 5...  Read Full »

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