Common "Pcr" queries answered by top doctors | iCliniq


PCR is the short form for a polymerase chain reaction. It is a method used to make copies of DNA or RNA in samples containing only minute quantities of both. This test is done to diagnose hereditary conditions, in DNA profiling, and the diagnosis of infectious disease.

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I have reactivated Epstein-Barr for a year. Please help.

Query: Hi doctor, I have had reactivated Epstein-Barr for a year. I recently got a blood test, which said, faint monoclonal band detected in the gamma region, repeat blood test in six months. There is no immunoparesis, and my levels have risen in the last four months, but still in the normal range. What do...  Read Full »

Dr. Shinas Hussain A. P

Answer: Hello, Welcome to I have gone through your query, and I can understand your concerns. The brief history you have described suggest a possibility of past infection with EBV (Ebstein-Barr virus). Probably you had an episode of IMN( infectious mononucleosis) in the childhood, which is ...  Read Full »

What does negative PCR and positive antigen tests for hepatitis C mean?

Query: Hello doctor, I want to know your opinion. I have had two positive hepatitis C antigen tests and the doctor had a polymerase chain reaction test that was negative for hepatitis C. He said I was one of the lucky ones. He said he could repeat and I did and again negative. All blood was concerning liv...  Read Full »

Dr. Goswami Parth Rajendragiri

Answer: Hi, Welcome to You had a history of laparotomy operation as a consequence of ruptured ectopic pregnancy. But none of the surgical management has been related to your low TSH level. TSH level can be altered in infective condition or sometimes temporary due to non-thyroid illness. I sug...  Read Full »

I have fatigue, increased saliva and throat pain months after unprotected sex. Why?

Query: Hello doctor,I had unprotected sex with a sex worker three and a half months ago. Two months later, I started having ARS symptoms, fatigue, diarrhea, dizziness, sore throat, and mouth ulcers. Just a day before that I had protected sex with a sex worker but my penis was not fully erect and did not in...  Read Full »

Dr. Kiran Anaparthi

Answer: Hi, Welcome to First, HIV symptoms are non-specific and are common to most infections and are referred to as flu-like symptoms. HIV infection symptoms in the acute phase often go undetected and are self-healed without any active intervention due to an intact immune system. These sympt...  Read Full »

I have high RBC count, low MCV, and MCH. Why?

Query: Hi doctor, If my complete blood count has high RBC value and low MCV and MCH values, what is the possible diagnosis for me?  Read Full »

Dr. Goswami Parth Rajendragiri

Answer: Hi, Welcome to 1. High RBC count is called polycythemia. If it is persistently high, then the cause should be evaluated. Respiratory causes like COPD (chronic obstructive pulmonary disease) and cardiac causes can lead to secondary polycythemia. Primary polycythemia is a myeloprolifera...  Read Full »

Which tests should I choose for STIs and HIV to be certain?

Query: Hi doctor, I had protected sex with a CSW (Commercial Sex Worker) five months before. I do not know the condom's status, either broken or ruptured. I was drunk that day, but I did not even ejaculate. Since I had a doubt, I took a test in the 4th week, HIV 1 and 2 antibody rapid tests from the labora...  Read Full »

Dr. Asmeet Kaur Sawhney

Answer: Hi, Welcome to I can understand your concern. You have gone for antibody testing for HIV (Human Immuno deficiency Virus) 1 and 2 many times, and it has come negative. When two tests for antibody detection based on different principles are negative, it means the individual is not having ...  Read Full »

My HIV tests fall under false negative. Can I have HIV?

Query: Hello doctor, My ex-partner had HIV (Human Immunodeficiency Virus) three years ago when I was along with him. But, he informed me regarding this very recently. He did not make me aware of his condition. We were not careful always. After getting to know, I checked on internet about its signs and symp...  Read Full »

Dr. Atishay Bukharia

Answer: Hi, Welcome to Out of nearly hundred person having sex with HIV (human immunodeficiency virus) positive person, hardly less than one may get infected. The chances of acquiring HIV after sexual exposure is less than one percent. I would suggest you to get HIV RT- PCR (reverse transcript...  Read Full »

Will quitting alcohol and cigarettes improve my blood tests?

Query: Hello doctor, I am suffering from hypertension since few years, and I am currently on medication Telmisartan. I am an alcoholic and smoker, and I smoke approximately 15 cigarettes a day for the last five years. My current CBC report suggests high RBC, hemoglobin, and PCV. Though it reduced slightly ...  Read Full »

Dr. Goswami Parth Rajendragiri

Answer: Hi,Welcome to have gone through your attached reports (attachment removed to protect patient identity).The diagnosis is polycythemia. Polycythemia can be secondary or primary. Secondary polycythemia occurs because of hypoxia, which activates the oxygen sensor and more erythropoietin is...  Read Full »

My HSV 1 IgG value is 49.20. Does it mean the infection is a recent one?

Query: Hello doctor, I took an STD panel test and got a positive result for HSV-1 IgG Ab test. My result was 49.20, but the reference range was 0.91 for negative and anything over 1.09 as positive. Does my 49.20 mean the infection is a very recent one because it is so high? I am confused about why it is s...  Read Full »

Dr. Sadaf Mustafa

Answer: Hello, Welcome to HSV (herpes simplex virus) IgG (immunoglobulin G) antibodies indicate previous exposure and HSV IgM (immunoglobulin M) indicates current disease. The positive IgG can become significant only if you have active lesions. The type one usually causes oral lesions which ...  Read Full »

I have a high platelet count. what could be the reason?

Query: Hi doctor, I am a 46-year-old diabetic female. My platelet count is high at 900,000 per microliter of blood in routine CBC. My iron is normal. My USG showed hepatosplenomegaly and PBS showed microcytic hypochromic anisocytosis. What shall I do now?  Read Full »

Dr. Veerendra Channabasappa Patil

Answer: Hello, Welcome to The platelet count is above the normal range. There are many reasons for such elevated platelet count. It needs further investigations, including genetic tests. The conditions like essential thrombocytosis could be considered with the available information from you....  Read Full »

My FIL's fever is not improving even after medications and antibiotics. Why?

Query: Hi doctor, My father-in-law is about 68 years old. For the last 12-13 days, he is having a fever of 101 to 102. We have shown him to the local physician. As prescribed, he is taking some medicine for fever with some antibiotics. The fever is going down on the effect of the medicine. However, the te...  Read Full »

Dr. Muhammad Zubayer Alam

Answer: Hi, Welcome to I can understand your concern. According to your statement, your father-in-law has been suffering from fever for the last 12-13 days, which is fluctuating in nature. The prescription and the investigation reports (attachment removed to protect patient identity)...  Read Full »

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