Recently Answered Questions
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I suspect having autoimmune disease. Please help.
Query: Hello doctor,Based on the following, do I have an autoimmune disease:An overall feeling of sickness.Irregular heartbeat sometimes.Swollen and painful joints.Swollen legs, ankles, fingers, and toes.Headaches sometimes.Shortness of breath.Psoriasis arthritis.Visual problems, burning, itching, very dry... Read Full »
Answer: Hello, Welcome to icliniq.com. I went through your post. Things which favor the diagnosis of autoimmune disease in your case are as follows: Pain and swelling of joints. Puffiness of hands and feet. Dryness of mouth and eyes. Psoriasis. You need to be investigated for UCTD (undifferentiated... Read Full »
Why my brother gets jaundice every year during summer?
Query: Hello doctor, My brother has jaundice, and it is occurring every year during summer. He feels very low and lazy, and his body becomes yellow. He is experiencing weakness and swelling on face and across his ankle. He also has a fever. We do not know why he gets sick every year. In addition to that, h... Read Full »
Answer: Hello, Welcome to icliniq.com. I went through your post and the investigations (attachment removed to protect patient identity) that you have posted. He has the following problems: Low platelet count of 40,000. Iron-deficiency anemia. Hepatospleenomegaly. Raised serum bilirubin and mild e... Read Full »
My hands hurt for no reason, and I doubt if an autoimmune disease is a reason. Can you please help?
Query: Hi doctor, I think I have an autoimmune disease. Hands hurt for no reason at all. I tested negative for sjogren's syndrome, lupus, and rheumatoid arthritis. I am tired all the time and have no appetite. I am currently taking tablet Lexapro (Escitalopram Oxalate), tablet Adderall (Dextroamphetamine S... Read Full »
Answer: Hi, Welcome to icliniq.com. Speckled antinuclear antibodies are seen in mixed connective tissue disease (MCTD) and scleroderma. If you have raynaud's phenomenon, do an echocardiogram (ECHO) to look for pulmonary artery hypertension, a high-resolution computed tomography (HRCT) of the chest to asse... Read Full »
Should I worry about joint instability, cracking, and high ANA titer?
Query: Hello doctor,Could you review my lab results to assess the likelihood of an autoimmune condition? My ANA titer is 1:1280 (homogeneous), and my RNP score has been 1.2 and 1.3 on two tests. My rheumatologist believes it is a false positive with benign antibodies, even at this high titer. Are they corr... Read Full »
Answer: Hi, Welcome to icliniq.com. I read your query and understand your concern. After reviewing the reports (attachments removed to protect the patient's identity), two key points stand out: a strongly positive ANA (antinuclear antibody) and the presence of arthritis (stiff joints). ANA results of this m... Read Full »
Is blood in my urine suggestive of kidney disease?
Query: Hello doctor, I had been experiencing extreme fatigue, brain fog, difficulty concentrating or remembering, muscle aches, mood swings, and frequent UTI (painful urination and sometimes blood) for years. I had a urine sample taken, and it always shows blood or protein in my sample, but no bacteria. I... Read Full »
Answer: Hi, Welcome to icliniq.com. I went through your post and laboratory tests (attachments removed to protect the patient's identity). I did not find anything suggestive of lupus (autoimmune disease). It looks like IgA (immunoglobulin A) nephropathy, which could be the reason for hematuria (presence o... Read Full »
Are my symptoms due to an infection or autoimmune disease?
Query: Hello doctor,Over the past year, I have had polyclonal B cell activation, raised IgM, and positive ANA (antinuclear antibodies) with systemic flu-like symptoms. However, doctors do not comment on anything because I have worsening symptoms. I experience fatigue, Raynaud's disease, skin rashes, petech... Read Full »
Answer: Hello, Welcome to icliniq.com. I went through your investigations (attachments removed to protect the patient's identity), and your symptoms suggest connective tissue disease. ANA (antinuclear antibody) test is positive, and you have oral ulcers, skin rash, and hair loss. All of them are suggestiv... Read Full »
I have autoantibodies in my blood and some related specific proteins. What could they indicate?
Query: Hello doctor, I have autoantibodies in my blood and some related specific proteins. I still do not have serious symptoms. I can send my results. Read Full »
Answer: Hello, Welcome to icliniq.com. I went through your post and investigations. There are a few significant results in the autoimmune profile. Your ANA (antinuclear antibody), dsDNA (double-stranded deoxyribonucleic acid), and anti-Ro are positive, which is suggestive of SLE (systemic lupus erythemato... Read Full »
Alpha 2 Globulin and Gamma Globulin are High. What Does This Mean?
Query: Hello doctor,I tested positive for an autoimmune disease. My titers were 1280. I then had more blood work done by a rheumatologist and just now received some back online. I noticed my alpha 2 globulin was high (1.12) and my gamma globulin was pretty high as well. The rest were normal on the protein ... Read Full »
Answer: Hello, Welcome to icliniq.com. You have not mentioned which autoimmune disease test has come positive. High levels of alpha 2 globulin are seen when there is a loss of albumin via urine because alpha 2 is a large molecule. It does not pass kidney filtration. So, it is retained because it is a ... Read Full »
My 28-year-old wife has been diagnosed with Wegener's granulomatosis. Is this disease curable?
Query: Hello doctor, I married a girl who is 28 years old now. We got married a year ago. She was diagnosed with Wegener's granulomatosis. She is taking medications and injections. I learned about the severity of the disease, so I started feeling low. I am attaching her blood work and reports. I need to kn... Read Full »
Answer: Hello, Welcome to icliniq.com. I have seen these reports (attachments removed to protect the patient's identity) in the past also. From these reports, I can say that she is in remission, which means the disease is under control. I understand your concern as the disease is lifelong, and once it is ... Read Full »