Blood Group

Blood group is the classification of blood according to the presence and absence of antibodies and inherited antigenic substances on the surface of the red blood cells. They are inherited from both parents. The most important blood group systems are ABO and Rh (rhesus factor) type. They determine other's blood types such as A, B, AB, and O with + or - denoting Rh status suitable for blood transfusion.

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Why does the bilirubin level keep changing in my 12-days-old son?

Query: Hi doctor, I am really concerned with the bilirubin levels of my 12 days old son. His bilirubin was 14.2 within 24 hours of his birth, so the doctor decided to start phototherapy, which reduced the bilirubin level to 12 and he got discharged. After a day, he turned pale yellow, so we rushed again to...  Read Full »

Dr. Veerabhadrudu Kuncham

Answer: Hi, Welcome to I understand that you are upset with your baby's condition. Your baby has ABO incompatibility (mother O and baby A blood group) induced exaggerated NNJ (neonatal jaundice). It is a condition where there will be an excessive breakdown of baby's red blood cells than compa...  Read Full »

Will the blood grouping test require 10 ml to 20 ml blood?

Query: Hello doctor, Recently, I went to a nearby hospital for blood grouping. I am concerned if blood grouping needs a whole syringe of blood as the technician did, or was he collecting my plasma for any other purpose without my consent. I am not sure if it was a 10 ml or a 20 ml syringe. Please help.  Read Full »

Dr. Arpit Varshney

Answer: Hello, Welcome to A technician collects more blood than required because sometimes the test for blood grouping gets errors and needs more blood. If he had taken only a tiny amount and an error occurred, you would have to give the sample again. So to avoid that, he took more than re...  Read Full »

My blood group has changed from B positive to B negative. Why?

Query: Hi doctor, My blood group has changed from B positive to B negative. During diagnosis, it is found that my lymphocyte count is higher, which is around 54%. I have some other problems like itching underarms and piles. My CT and PET scan report are normal. Ultrasound report shows fatty liver. Why has...  Read Full »

Dr. Parth R Goswami

Answer: Hi, Welcome to I understand your concern. Blood group never changes throughout life. I suggest you get your blood group checked in a good blood bank. One of your blood groups might be false due to a faulty technique. Hope I have answered your question. Underarm itching might be due t...  Read Full »

Is it normal to have both positive and negative blood?

Query: Hi doctor, When I was 17, I donated blood. They sent me a card with my blood type B positive. When I was pregnant, the first time they tested it twice and told me it was B negative. I thought the donation test had been wrong. After my second child, my doctor upon hearing this story checked my blood ...  Read Full »

Dr. Ramesh Kumar S

Answer: Hi,Welcome to person who has more than one set of DNA is a chimera, and the condition is called chimerism.Chimerism usually does not cause problems. It is rarely diagnosed and making it hard for scientists to say how prevalent the phenomenon truly is.It is probably less rare than was o...  Read Full »

I got married to my relative, having the same blood group. Do I need to worry about my second baby?

Query: Hi doctor, I got married to my relative and we have the same blood group. My first baby is quite healthy and fine without any problem. Now, we are planning for the second baby. We did not check about Rh factor yet and we afraid that any problem might come in the second pregnancy. Should I worry a...  Read Full »

Dr. Parth R Goswami

Answer: Hi, Welcome to You and your husband are relatives, so in such situation prenatal or preconception counseling is beneficial to avoid the consanguineous disease transmission mainly autosomal recessive problem like thalassemia. If your blood group is Rh negative and if the fetus is Rh pos...  Read Full »

What problems occur when a couple has different Rh factor?

Query: Hi doctor,My blood group is B positive. I am going to marry a person with B negative blood group. Is there any problem?  Read Full »

Dr. Parth R Goswami

Answer: Hi, Welcome to I can understand your concern. From history, I hope you are telling that you (male) is B positive and your fiance (female) is B negative.According to Rh grouping, a person can have Rh positive or Rh negative group. You both can marry and can produce a ...  Read Full »

My fiance's blood group and mine are different. Will it create problems to our baby's health?

Query: Hi doctor, My blood group is AB+, and my fiance's blood group is AB-. Will different blood groups create problems in future, regarding baby's health or other issues?  Read Full »

Dr. Parth R Goswami

Answer: Hi, Welcome to You and your fiance can marry without any problem. Do not worry regarding that. The only thing that has to be done is checking the baby's blood group. As your blood group is Rh negative, so if the baby's blood group is Rh positive then it might lead to Rh in...  Read Full »

Why does my newborn baby have high bilirubin?

Query: Hi doctor,Our newborn baby was found to have serum bilirubin 20 and direct 18 on the 4th day. Kindly suggest appropriate advice. If we are going for photo therapy, then which light is better?  Read Full »

Dr. Deepak Patel

Answer: Hi, Welcome to I can understand your concerns. Serum bilirubin of 20 is high for the baby. The value of 18 mg/dL should be indirect bilirubin, because indirect bilirubin is increased in most cases. If direct bilirubin is so much, then the treatment is different. If it is indirect biliru...  Read Full »

Can two O positive blood group people get married?

Query: Hi doctor, I am 30 years old. I am planning to get married to a girl who is known to me. We have very good understanding. But, we have the same blood group that is O positive. Since blood group is a factor for having babies, do you think having same positive blood group could create problems for fut...  Read Full »

Dr. Prakash H. Muddegowda

Answer: Hi, Welcome to Based on your query, my opinion is as follows: There are two major blood group systems and more than 400 minor blood group systems. The major blood group systems are ABO system and Rhesus system, which are important. In the ABO system, there is A, B, AB and O. While in Rh...  Read Full »

Is marrying a partner with same blood group harmful?

Query: Hello doctor, Blood group of the male is A positive and blood group of the female is A with Rh positive. Can they get married? Will they face any problem in getting pregnant?  Read Full »

Dr. Parth R Goswami

Answer: Hi, Welcome to There is no harm in marrying the partner of same blood group. Every individual has unique own blood group and ABO and Rh system used most commonly. If you want to do preconception counseling then investigate with CBC (complete blood count) and if needed HPLC (high-per...  Read Full »

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